Insomnia hazards
Physiological experiments have shown that people who lack sleep not only have a significant decrease in immune function, but also have 4-5 times the daily aging process compared to normal people. The following article systematically explores and studies the impact of sleep on physiological tissues:
1. Sleep and cell lifespan
The consequences of lack of sleep on cellular oxidative renewal mainly lead to tissue damage, which is repaired through the action of enzymes. Continuous repair between molecules and the overall maximum lifespan of cells are inseparable. In terms of aging, the most important thing is to detect DNA damage and repair them, and the integrity of cells is the foundation of their division and proliferation lifespan, And this repair mechanism is completed during deep sleep in living organisms.
Scientific research experiments have shown that high intensity sleep time is the most powerful force that the average body spends on repairing DNA damage. In terms of cellular molecular science, this balance between DNA damage and DNA repair is the most important indicator of Cellular senescence.
2. Sleep and body immunity
Whether it is a lack of sleep or a lack of complete sleep, it is a devastating blow to the human immune system, with the thymus gland rapidly shrinking. This is the most important immune organ in the human body. Normally, only in the middle and old age will the thymus shrink to the size of a cherry, while the proliferation of T cells will significantly decrease. Not only will white blood cells and lymphocytes be greatly reduced, but macrophages will also have an inhibitory effect.
Without the protection of the immune system in the human body, the threat of various carcinogenic diseases to the human body can be said to be fatal. Even in the short term, the human body may feel nausea, dizziness, mental atrophy, and limb weakness, which is not only a physiological trend of a direct decline in immunity, but also a precursor to diseases.
3. Sleep and nervous system
The nervous system is the main functional regulation system of the body, which directly regulates the functions of various organs and systems in the body, and sleep is closely related to the physiological role of the central nervous system,
As a regulatory mechanism, sleep is used to regulate visceral activity and hormone secretion through the hypothalamus, The neuroendocrine not only depends on the instructions of the central nervous system, but also is the activity cycle of the "Circadian clock" of life itself.
Physiologically, the Circadian clock is the memory code that DNA plays the role of heredity. The following thalamus tissue will secrete reducing glutathione, Superoxide dismutase (SOD) and so on from 10 o'clock to about at night when the human body is in deep sleep. These are non synthetic human essential hormones, which are mainly used to repair cell damage, promote cell proliferation and differentiation, and ensure the normal growth and development of various tissues and organs.
4. Sleep and repair mechanisms
Experiments have shown that even short-term sleep deprivation and lack of sufficient sleep time can lead to rapid aging and a significant decrease in the body's immune system.
Deep sleep at night, through the central nervous system of the hypothalamus, actually regulates the metabolic activities of various tissue cells to affect the physiological activities of the human body, mainly used to repair cell damage and restore the integrity of tissue function.
Circadian clock